Carlos J Pirola Selected Research

pro-thyrotropin releasing hormone

8/2008	Thyrotropin-releasing hormone precursor gene knocking down impedes melanocortin-induced hypertension in rats.
5/2007	Knocking down the diencephalic thyrotropin-releasing hormone precursor gene normalizes obesity-induced hypertension in the rat.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Carlos J Pirola Research Topics

Disease

47	Non-alcoholic Fatty Liver Disease 10/2022 - 09/2009
13	Fatty Liver 10/2020 - 09/2009
12	Insulin Resistance 05/2022 - 12/2005
11	Metabolic Syndrome (Dysmetabolic Syndrome X) 05/2022 - 10/2005
11	Hypertension (High Blood Pressure) 02/2016 - 02/2002
9	Obesity 08/2012 - 02/2002
8	Fibrosis (Cirrhosis) 11/2022 - 03/2005
6	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 01/2013
4	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022 - 10/2011
4	Type 2 Diabetes Mellitus (MODY) 09/2018 - 01/2010
3	Inflammation (Inflammations) 11/2022 - 02/2015
3	Liver Diseases (Liver Disease) 01/2022 - 07/2014
3	Genetic Predisposition to Disease (Genetic Predisposition) 01/2021 - 11/2012
2	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 07/2014
2	Neoplasms (Cancer) 01/2022 - 06/2005
2	Liver Neoplasms (Liver Cancer) 01/2021 - 04/2018
2	COVID-19 10/2020 - 01/2020
2	Mitochondrial Diseases (Mitochondrial Disease) 12/2016 - 07/2014
2	Atherosclerosis 05/2015 - 10/2011
2	Intrahepatic Cholestasis of Pregnancy 01/2014 - 01/2008
1	Morbid Obesity 09/2018
1	Neoplasm Metastasis (Metastasis) 06/2018
1	Adenocarcinoma of Lung 06/2018
1	Body Weight (Weight, Body) 11/2017
1	Isolated Systolic Hypertension 02/2016
1	Alcoholic Fatty Liver 05/2015

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 01/2021 - 10/2011
9	Insulin (Novolin)FDA Link 11/2017 - 10/2005
8	EnzymesIBA 04/2017 - 08/2012
7	Biomarkers (Surrogate Marker)IBA 01/2022 - 08/2012
7	Triglycerides (Triacylglycerol)IBA 11/2017 - 10/2005
7	LeptinIBA 11/2017 - 02/2002
5	Phospholipases (Phospholipase)IBA 11/2022 - 06/2011
5	LipidsIBA 01/2021 - 09/2009
5	Mitochondrial DNA (mtDNA)IBA 12/2016 - 07/2008
4	Transaminases (Aminotransferases)IBA 08/2019 - 01/2015
4	Amino Acids FDA Link 01/2018 - 08/2012
4	Glucose (Dextrose)FDA LinkGeneric 11/2017 - 10/2005
4	Messenger RNA (mRNA)IBA 02/2016 - 02/2005
3	MicroRNAs (MicroRNA)IBA 01/2022 - 05/2015
3	Pharmaceutical PreparationsIBA 01/2021 - 01/2019
3	Biological ProductsIBA 01/2021 - 10/2020
3	Oxidoreductases (Dehydrogenase)IBA 01/2020 - 01/2019
3	DNA (Deoxyribonucleic Acid)IBA 09/2015 - 05/2010
3	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 10/2011 - 02/2003
2	GlucokinaseIBA 01/2020 - 09/2018
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2020 - 10/2011
2	Long Noncoding RNAIBA 06/2018 - 04/2017
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 02/2016 - 08/2012
2	LDL CholesterolIBA 12/2015 - 10/2005
2	Alanine (L-Alanine)FDA Link 01/2015 - 08/2012
2	Bile Acids and Salts (Bile Acids)IBA 01/2014 - 12/2010
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2013 - 12/2010
2	P-2 (P 2)IBA 06/2011 - 12/2010
2	Thyrotropin-Releasing Hormone (Protirelin)FDA Link 01/2011 - 02/2002
2	mitochondrial transcription factor AIBA 12/2010 - 05/2010
2	Type 1 Angiotensin ReceptorIBA 09/2009 - 03/2005
2	Losartan (Cozaar)FDA LinkGeneric 09/2009 - 03/2005
2	pro-thyrotropin releasing hormoneIBA 08/2008 - 05/2007
2	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 02/2008 - 02/2007
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2005 - 10/2005
2	AngiotensinogenIBA 03/2005 - 02/2003
1	Uric Acid (Urate)IBA 05/2022
1	CreatinineIBA 05/2022
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 05/2022
1	ChromatinIBA 01/2022
1	Bacterial DNAIBA 06/2021
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2021
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2021
1	Ketone BodiesIBA 01/2021
1	LigandsIBA 01/2021
1	SeleniumIBA 01/2021
1	SphingolipidsIBA 01/2021
1	Arachidonic Acid (Vitamin F)IBA 01/2021
1	MicronutrientsIBA 01/2021
1	Pyruvic Acid (Pyruvate)IBA 01/2021
1	ProteomeIBA 10/2020
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 01/2020
1	AcyltransferasesIBA 01/2020
1	Anti-Infective Agents (Microbicides)IBA 01/2019
1	PhytochemicalsIBA 01/2019
1	Adenine FDA LinkGeneric 01/2019
1	Nonsense Codon (Nonsense Mutation)IBA 09/2018
1	CytokinesIBA 03/2018
1	AdipokinesIBA 03/2018
1	Cell-Free Nucleic AcidsIBA 04/2017
1	Dimethylglycine DehydrogenaseIBA 01/2017
1	Betaine (C.B.B.)FDA Link 01/2017
1	2- (2,6- dimethyl- 4- (3- (4- (methylthio)phenyl)- 3- oxo- 1- propenyl)phenoxyl)- 2- methylpropanoic acidIBA 07/2016
1	HSP27 Heat-Shock ProteinsIBA 03/2016
1	Protein Isoforms (Isoforms)IBA 02/2016
1	3' Untranslated Regions (3' UTR)IBA 02/2016
1	CholesterolIBA 12/2015
1	oxidized low density lipoproteinIBA 12/2015
1	ImmunosorbentsIBA 09/2015
1	Circulating MicroRNAIBA 05/2015

Therapy/Procedure

5	Precision Medicine 10/2022 - 08/2012
4	Therapeutics 10/2020 - 01/2013
1	Bariatric Surgery 01/2021
1	Drug Therapy (Chemotherapy) 08/2019